It all depends on who you are handcuffing. If you have an injury prone stud like Alexander, then you must handcuff. Also, it is dependent on the quality of the backup. there are a few 2nd string guys that are better than some starters. A prime example is Derrick Ward of the Giants and Selvin Young in Denver. Young's benefits havent really been seen yet, but come fantasy playoff time, he will be highly coveted.
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